Improved Clinical Outcome of Digoxin Toxicity Despite Increased Serum Potassium Levels

good outcome after digoxin toxicity despite very high serum potassium level

Good Outcome after Digoxin Toxicity Despite Very High Serum Potassium Level

Dear Editor, Digoxin, as a cardiac glycoside extracted from the Digitalis lanata is widely used in the treatment of different heart diseases, such as atrial fibrillation, atrial flutter and heart failure. Its effect is to increase myocardial contractility while mildly prolonging the duration of contraction. The result is decreased heart rate, increased blood pressure and stroke volume, leading ...

Digoxin toxicity with normal digoxin and serum potassium levels: beware of magnesium, the hidden malefactor.

BACKGROUND In recent years, digoxin use has been on the decline, with decreased incidence of digoxin toxicity. Hence, digoxin toxicity, when it occurs, remains an elusive diagnosis to emergency physicians. OBJECTIVE To present a case of digoxin toxicity with normal levels of digoxin and serum potassium, but with severe hypomagnesemia. CASE REPORT A 66-year-old woman presented with junctiona...

A correlative study of serum digoxin levels with clinical tolerance.

In a series of 102 digitalised patients serum digoxin levels (SDL) were determined by radioimmunoassay (RIA). Age categorisation included juveniles (15%), adults (67%) and geriatrics (18%). Clinical categorisation included loading, adequate, inadequate, toxic, and borderline digitalisation groups. The mean SDL in the toxic-group was 3 .93 ng/ml (S.D. 1.40), and in the nontoxic group 1.27 ng/ml ...

Digoxin toxicity: clinical and laboratory assessment.

A prospective study to correlate clinical digoxin toxicity with serum digoxin levels was carried out in 67 patients of whom 24 were clinically toxic and 43 were asymptomatic. The patients were clinically diagnosed to be toxic based on typical cardiac arrhythmias (n = 11) or non-cardiac symptoms (n = 13). Blood samples were collected at least six hours after the last digoxin dose and the sera as...